abstract：PURPOSE:This prospective, multicenter study was initiated to evaluate the diagnostic performance of PSA, free/total PSA (f/tPSA) and complexed PSA (cPSA) with volume-based parameters for early detection of prostate cancer in patients with PSA between 2.5 and 20 ng/ml. MATERIALS AND METHODS:408 subjects with serum PSA ...

journal_title：European urology

authors： Sözen S,Eskicorapci S,Küpeli B,Irkilata L,Altinel M,Ozer G,Uygur C,Alkibay T,Ozen H

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:The retroperitoneal laparoscopic approach is utilized to treat a right renal tumor with vena caval thrombus reaching infrahepatic veins. MATERIALS AND METHODS:The patient is an 87-year-old woman with a tumor measuring 8 x 9 cm and a vena caval thrombus (7 cm), stretching as far as the subhepatic vein. The retr...

journal_title：European urology

authors： Disanto V,Pansadoro V,Portoghese F,Scalese GA,Romano M

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To determine the most suitable type of graft-free penile skin grafts or mucosal grafts from bladder or buccal regions - for urethral reconstruction in an animal model, as evaluated on the basis of angiogenic activity. METHODS:Twenty-two male White New Zealand rabbits were randomly divided into four groups. I...

journal_title：European urology

authors： Gardikis S,Giatromanolaki A,Ypsilantis P,Botaitis S,Perente S,Kambouri A,Efstathiou E,Antypas S,Polychronidis A,Touloupidis S,Sivridis E,Simopoulos C

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:We prospectively evaluated the learning curve (LC) of laparoscopic radical prostatectomy (L-RPE) regarding the improvements in operative times (OT) and technical difficulty in one-operator-practice as it compares with open RPE. METHODS:Over 18 months, 50 L-RPE were performed by an inexperienced surgeon in la...

journal_title：European urology

authors： Poulakis V,Dillenburg W,Moeckel M,de Vries R,Witzsch U,Zumbé J,Rassweiler J,Becht E

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:We retrospectively evaluated the safety, efficacy and patient satisfaction following the male sling procedure for stress urinary incontinence. MATERIALS AND METHODS:Forty-six patients, with a median age of 67 years, underwent the perineal male sling procedure for stress urinary incontinence. Radical retropub...

journal_title：European urology

authors： Rajpurkar AD,Onur R,Singla A

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:Multifocality and frequent recurrence of urothelial carcinoma of the urinary bladder indicate a disease of the entire "urothelial field", but little is known about chromosomal alterations in histologically normal urothelium. Histopathologically normal urothelium from patients with and without concurrent urot...

journal_title：European urology

authors： Stoehr R,Zietz S,Burger M,Filbeck T,Denzinger S,Obermann EC,Hammerschmied C,Wieland WF,Knuechel R,Hartmann A

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:In women, aging is associated with profound hormonal changes. Menopause has been implicated in the etiology of urinary tract complaints including incontinence, urgency and recurrent urinary tract infections. However, the use of hormone replacement therapy for these conditions has given conflicting and disapp...

journal_title：European urology

authors： Blanchet P,Yaici el-D,Cayzergues L,Giuliano F,Jardin A,Benoit G,Droupy S

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:With current treatments, men usually survive many years after being diagnosed with prostate cancer. However, without supportive care, the systemic effects of prostate cancer and therapies such as androgen deprivation therapy (ADT) can undermine skeletal integrity, resulting in skeletal complications that may ...

journal_title：European urology

authors： Saad F,Olsson C,Schulman CC

更新日期：2004-12-01 00:00:00

abstract：PURPOSE:The cellular mechanisms involved in unstable uncontrolled detrusor contractions in the human bladder remain unknown. One hypothesis, based on electron microscopical observations and animal studies, is that gap junctions are present in the human detrusor and are increased in patients with detrusor overactivity. ...

journal_title：European urology

authors： Haferkamp A,Mundhenk J,Bastian PJ,Reitz A,Dörsam J,Pannek J,Schumacher S,Schurch B,Büttner R,Müller SC

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:Assessment of the long-term morbidity of the upper urinary tract and of the voiding pattern in men with an ileal orthotopic bladder substitute with an afferent tubular segment. MATERIALS AND METHODS:Men surviving more than 5 years after radical cystectomy and orthotopic bladder substitution were evaluated. T...

journal_title：European urology

authors： Perimenis P,Burkhard FC,Kessler TM,Gramann T,Studer UE

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:Prostate cancer is a leading cause of cancer-related mortality and morbidity in Western world. Curative treatment is feasible provided the disease is diagnosed in its earliest stages, but current screening methodologies are characterized by low specificity. DNA-based markers are a class of new and promising t...

journal_title：European urology

authors： Henrique R,Jerónimo C

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:To assess the training and the general and financial conditions of European residents in urology. METHODS:Between February and April 2004 a questionnaire was sent by e-mail to 351 residents in urology in 30 different European countries. The questionnaire was divided into four different sections concerning ge...

journal_title：European urology

authors： Ballario R,Rubilotta E

更新日期：2004-10-01 00:00:00

abstract：PURPOSE:Based on the experience of 1000 cases of laparoscopic radical prostatectomy, we compared the operative parameters of transperitoneal and extraperitoneal approaches in match-paired patient groups. PATIENTS AND METHODS:We reviewed the charts of 53 consecutive patients who underwent selectively extraperitoneal la...

journal_title：European urology

authors： Erdogru T,Teber D,Frede T,Marrero R,Hammady A,Seemann O,Rassweiler J

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:The methodology of corpus cavernosum electromyography (CC-EMG) was revisited, in order to overcome current methodological difficulties that hinder its clinical application. MATERIALS AND METHODS:Using an 8-channel device, CC-EMG was performed in 12 healthy volunteers. Surface electrodes were placed bilateral...

journal_title：European urology

authors： Jiang XG,Wijkstra H,Meuleman EJ,Wagner G

更新日期：2004-09-01 00:00:00

abstract：:Appropriate handling and processing of prostate needle biopsies is critical for an optimal examination by pathologists. Reporting by pathologists should be accurate, unequivocal and concise, giving the information needed for the urologist. Quality parameters need to be developed to survey the performance of pathology ...

journal_title：European urology

authors： Boccon-Gibod L,van der Kwast TH,Montironi R,Boccon-Gibod L,Bono A,European Society of Uropathology.,European Society of Pathology Uropathology Working Group.

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:The long-term outcome of artificial urinary sphincter (AUS) is unpredictable because of, among others, the risk of breakdown of one of its components. Our objective was to define a strategy for an accurate diagnosis and an appropriate management of these problems. PATIENTS AND METHODS:From 1985 to 2000, 298 ...

journal_title：European urology

authors： Maillet F,Buzelin JM,Bouchot O,Karam G

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:To determine the efficacy and tolerability of flexible dosing with vardenafil in a broad population of men with erectile dysfunction (ED). METHODS:10-week, open-label, flexible-dose study starting with vardenafil 10 mg, titrating to 5 mg or 20 mg at weeks 2 and 6 based on efficacy and tolerability, set in 78...

journal_title：European urology

authors： Potempa AJ,Ulbrich E,Bernard I,Beneke M,Vardenafil Study Group.

更新日期：2004-07-01 00:00:00

abstract：:The foundations of the generally accepted principles underlying the surgical management of renal cell carcinoma (RCC) were best annunciated in 1969 by Robson in his classic description of the radical nephrectomy [J Urol 1969;101;297]. Since then, much has changed in our understanding of the basic biology and genetics ...

journal_title：European urology

authors： Lam JS,Shvarts O,Pantuck AJ

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVES:The association between the severity of LUTS and prostate volume, prostate-related variables and general life-style factors was investigated in a large number of patients with persistent LUTS suggestive of BPH (LUTS/BPH). METHODS:Patients with LUTS/BPH aged between 50 and 80 years, were enrolled in this Ita...

journal_title：European urology

authors： Tubaro A,La Vecchia C,Uroscreening Study Group.

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the relationship between neuroendocrine differentiation (NED) status and hormone refractory prostate cancer (HRPC) following hormone therapy based on immunohistochemical study. METHODS:Seventy-two prostate cancer specimens obtained at radical prostatectomy and 21 prostate cancer autopsy specimens...

journal_title：European urology

authors： Hirano D,Okada Y,Minei S,Takimoto Y,Nemoto N

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE(S):The aim of our retrospective study was to determine if systematic placement of a posterior mesh, in addition to an anterior vesico-vaginal mesh, is necessary for laparoscopic treatment of pelvic organ prolapse. METHODS:A laparoscopic promontory sacral colpopexy was performed in 108 patients, including 55 ...

journal_title：European urology

authors： Antiphon P,Elard S,Benyoussef A,Fofana M,Yiou R,Gettman M,Hoznek A,Vordos D,Chopin DK,Abbou CC

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:Treatment of patients with mucosal prostatic urethral transitional cell carcinoma (TCC) is controversial. In this study, we evaluated the outcome of patients with mucosal prostatic urethral TCC who were managed conservatively. METHODS:The data of 290 consecutive male patients with superficial TCC of the blad...

journal_title：European urology

authors： Canda AE,Tuzel E,Mungan MU,Yorukoglu K,Kirkali Z

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:The objective of this research is to identify and determine the relative importance of dietary and environmental risk and risk reduction factors for prostate cancer mortality. MATERIALS AND METHODS:A multicountry ecologic approach was used in multivariate regression analyses with prostate cancer mortality ra...

journal_title：European urology

authors： Grant WB

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:To assess the long-term safety and tolerability of tadalafil for patients with erectile dysfunction (ED). PATIENTS AND METHODS:This was a multicentre, open-label, 24-month extension trial involving 1173 men with ED. The mean age was 57 (range 23-83) years and 74.8% of patients were taking concomitant medicat...

journal_title：European urology

authors： Montorsi F,Verheyden B,Meuleman E,Jünemann KP,Moncada I,Valiquette L,Casabé A,Pacheco C,Denne J,Knight J,Segal S,Watkins VS

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the cumulative risk of having a prostate cancer diagnosis in a repeated screening situation in relation to the free-to-total prostate specific antigen ratio (F/T-PSA). PATIENTS AND METHODS:The present study includes 1385 men (aged 50-70 years) who underwent prostate biopsy for the first time in t...

journal_title：European urology

authors： Aus G,Becker C,Franzén S,Lilja H,Lodding P,Hugosson J

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To assess the feasibility and efficacy of porcine skin collagen (Pelvicol) implant by the transobturator route for the treatment of anterior vaginal wall prolapse. PATIENTS AND METHODS:Twenty-seven women with stage III or IV prolapse underwent anterior vaginal wall repair with porcine skin collagen implantat...

journal_title：European urology

authors： Salomon LJ,Detchev R,Barranger E,Cortez A,Callard P,Darai E

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVES:To review the evidence underlying the diagnosis, pathology and treatment of lymphoedema of the lower extremities and genitalia from or following the treatment for urological cancer, and to suggest possible underlying pathophysiological mechanisms that may explain its development. METHODS:Reviews of the epid...

journal_title：European urology

authors： Okeke AA,Bates DO,Gillatt DA

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:A new surgical method of treating Peyronie's disease consisting in intracavernosal excision of the plaque is presented. MATERIAL AND METHODS:The operation was performed on 16 men aged from 34 to 65 years (mean 50.2 years). The angle of penile curvature was 30 degrees to 60 degrees. Thirteen (81.25%) had impa...

journal_title：European urology

authors： Darewicz JS,Darewicz BA,Galek LM,Kudelski J,Badri BM

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and toxicity of gemcitabine plus vinorelbine chemotherapy in patients with advanced bladder carcinoma who are unsuitable for or who have failed cisplatin-containing chemotherapy. PATIENTS AND METHODS:Thirty-one patients with advanced transitional cell carcinoma (TCC) of the bladder w...

journal_title：European urology

authors： Türkölmez K,Bedük Y,Baltaci S,Göğüş C,Göğüş O

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:The role of estrogens and androgens in the etiology and progression of testicular germ cell cancer is poorly understood. To gain insight into the role of sex steroid action in testicular tumorigenesis, we have measured mRNAs encoding estrogen receptor beta (ERbeta), androgen receptor (AR), and their coregulat...

journal_title：European urology

authors： Hirvonen-Santti SJ,Rannikko A,Santti H,Savolainen S,Nyberg M,Jänne OA,Palvimo JJ

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVES:To assess the feasibility of methylation-specific PCR (MSP) for the detection of promoter hypermethylation of the detoxifying glutathione-S-transferase P1 gene (GSTP1) to detect occult prostate cancer cells in lymph nodes (LNs). METHODS:Paraffin-embedded pelvic LNs from 20 patients with pT2pN0M0R0 prostate ...

journal_title：European urology

authors： Köllermann J,Müller M,Goessl C,Krause H,Helpap B,Pantel K,Miller K

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVES:Based on a recently introduced mathematical model approach we show that uroliths located in the urinary tract (UT) can substantially deplete the urinary concentrations of lithogenic constituents by continuous growth. METHODS:To illustrate the influence of the urinary depletion effect on urinalysis, a "typic...

journal_title：European urology

authors： Laube N,Pullmann M,Hergarten S,Schmidt M,Hesse A

更新日期：2003-11-01 00:00:00

abstract：:Pain is the most common symptom of any illness; the physician's therapeutic task is twofold: to discover and treat the cause of pain and the pain itself, whether or not the underlying cause is treatable, to provide relief and reduce the suffering caused by pain. Although we use the term of pain to define all sensation...

journal_title：European urology

authors： Francesca F,Bader P,Echtle D,Giunta F,Williams J,EAU.

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:The effects of intratumoral ethanol injection on renal cell carcinoma (RCC) heterotransplanted in nude rats were evaluated. MATERIALS AND METHODS:The OUR95AF human RCC cell line was inoculated subcutaneously into the backs of nude rats. Four weeks after transplantation, the size of tumors became 1.5-2.0 cm i...

journal_title：European urology

authors： Naitoh Y,Kawauchi A,Mizutani Y,Ukimura O,Fujito A,Nakao M,Kojima Y,Nonomura N,Okuyama A,Miki T

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To investigate whether unilaterally orchiectomised testicular cancer survivors (TCSs) are more likely to display reduced Leydig cell function than healthy males. METHODS:A national multi-centre survey of 1235 TCSs was performed in 1998-2000 (mean age: 44 years) treated between 1980 and 1994 (mean follow-up: ...

journal_title：European urology

authors： Nord C,Bjøro T,Ellingsen D,Mykletun A,Dahl O,Klepp O,Bremnes RM,Wist E,Fosså SD

更新日期：2003-09-01 00:00:00

abstract：PURPOSE:To evaluate the impact of androgen deprivation on health related quality of life (HRQOL) in patients with asymptomatic lymph node positive prostatic carcinoma (LPPC). MATERIALS AND METHODS:HRQOL domains were measured, using standard instruments in 91 patients with histologically proven LPPC. Most patients were...

journal_title：European urology

authors： van Andel G,Kurth KH

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVES:To determine the incidence and clinical relevance of newly diagnosed cases of prostate cancer in a group of men who had an elevated PSA and benign prostate biopsy 7 years previously. PATIENTS AND METHOD:Patients under the age of 80 years with an elevated PSA who had had a benign prostate biopsy in the 12 mo...

journal_title：European urology

authors： Boddy JL,Pike DJ,Malone PR

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:TUNA has been demonstrated to be a safe and effective therapy for BPH. However the major criticism, as with all alternative treatments for BPH, was the lack of long-term data. We present the clinical outcome of patients treated by TUNA and followed for 5 years. METHODS:188 consecutive patients with symptomat...

journal_title：European urology

authors： Zlotta AR,Giannakopoulos X,Maehlum O,Ostrem T,Schulman CC

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVES:Children with neurogenic hyper-reflexive bladder in whom classical therapy with anticholinergic drugs and intermittent catheterization fails are threatened by high intravesical pressure, vesicoureteral reflux, and impairment of kidney function. Surgery, such as bladder augmentation, is often necessary in suc...

journal_title：European urology

authors： Schulte-Baukloh H,Michael T,Stürzebecher B,Knispel HH

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVES:To examine the association between the complexed-to-total (C:T) prostate-specific antigen (PSA) ratio and prostate cancer pathological stage to assess whether the C:T PSA ratio may predict the final pathological stage in patients with clinically localized prostate cancer. PATIENTS AND METHODS:In a prospecti...

journal_title：European urology

authors： Martínez M,Navarro S,Medina P,Villavicencio H,Rioja L,Solsona E,Estellés A,Aznar J,Jiménez-Cruz JF,España F

更新日期：2003-06-01 00:00:00